The Agilent GC-APCI ion source enables rapid switching between GC/MS and LC/MS operation and the ability to analyze a wide diversity of matrices for applications such as environmental analysis, pesticides, and metabolomics – which often require two or more analyses on different mass spectrometers. While the non-volatile relatively polar compounds are usually separated by LC/MS, the more volatile non-polar compounds require GC/MS analysis. Adding GC-APCI capability to the TOF or Q-TOF LC/MS system provides the flexibility to perform high mass accuracy and high resolution quantitative and qualitative analysis of both semi-volatile and volatile compounds on a single instrument, saving time, money and bench space.